Ito C, Itoigawa M, Mishina Y, Tomiyasu H, Litaudon M, Cosson JP, Mukainaka T,
Tokuda H, Nishino H, Furukawa H.
Cancer chemopreventive agents. New depsidones from Garcinia plants
J Nat Prod 2001 Feb;64(2):147-50
Résumé : In a search for cancer chemopreventive agents from natural sources, chemical constituents of two kinds of Garcinia plants, Garcinia neglecta and Garcinia puat, collected in New-Caledonia, were examined.
Five new depsidones, garcinisidone-B (2), -C (3), -D (4), -E (5), and -F (6), were isolated, and their structures were
determined by spectrometric analyses. Inhibitory effects of these depsidones on EBV-EA activation induced by TPA in Raji cells were also demonstrated.
Depsidones actuellement recherchées notamment dans les lichens comme antiseptiques, antibactériens ou antimitotiques.
